Clonidine is a prescription medication that acts as a centrally acting alpha-2 adrenergic agonist, reducing sympathetic outflow and lowering blood pressure. Common Uses of Clonidine Use CaseDescription Hypertension (High Blood Pressure) Often used when other antihypertensives are not effective alone. ADHD (Attention Deficit Hyperactivity Disorder) Used especially in children, alone or as an adjunct. Opioid Withdrawal Helps reduce symptoms such as anxiety, agitation, sweating. Alcohol/Nicotine Withdrawal Off-label use to manage withdrawal symptoms. Sleep Disorders Occasionally used off-label for insomnia, especially in children. Menopausal Hot Flashes Off-label to reduce vasomotor symptoms. Tourette’s Syndrome Sometimes used to manage tics in children. Typical Dosage
