Increase desire with PT-141 nasal spray
PT-141 nasal spray for enhanced intimacy

PT‑141 Nasal Spray (Bremelanotide)

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Reignite Desire. Rebuild Confidence.

$139 first month

then $189/mo*

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Enhances sexual desire & arousal​

Works for both men and women

Rapid-acting, non-hormonal peptide

No Needles. Fast absorption.

Increases sensitivity and satisfaction

No hidden fees.

$139 first month

then $189/mo*

3-Month Plan

$169 first month

then $219/mo*

Monthly Plan

PT‑141, also known as bremelanotide, modulates melanocortin pathways in the brain involved in sexual arousal and desire. Unlike PDE5 inhibitors (e.g., sildenafil), which primarily affect blood flow, PT‑141 targets central mechanisms of desire and can be considered for adult men and women when appropriate.

For Women
  • Supports sexual desire and interest. 
  • On‑demand option separate from daily pills.
  • May be considered for pre‑ or post‑menopausal adults if clinically appropriate.

Some patients also explore Oxytocin therapy when their clinician determines that bonding-response pathways may play a role.

For Men
  • A desire‑focused option distinct from traditional ED pills.
  • Can be considered when blood‑flow medications aren’t a fit or as advised by a clinician.
  • Stack discussions (e.g., with tadalafil) should be clinician‑guided.

For men who prefer stimulation-based hormone support, Enclomiphene is another option that may be discussed when evaluating causes of low desire.

PT-141 comes in two forms: a nasal spray and a subcutaneous injection. Both are taken on-demand as directed. The nasal spray delivers the medication intranasally, making it a good fit for anyone who prefers a needle-free option. The injectable version uses a small, guided subcutaneous injection, ideal for people who are comfortable with quick self-injections. Regardless of which you choose, storage follows the instructions on your pharmacy label.

Always follow your clinician’s prescription directions and the pharmacy label. PT‑141 is typically used on‑demand; frequency limits and spacing rules apply for safety. Do not exceed more than one on‑demand dose within a 24‑hour period. Your prescriber may set additional monthly limits; follow their guidance strictly.

Good‑Use Checklist
  • Use only as prescribed and only for yourself.
  • Avoid repeating a dose sooner than directed.
  • Store and handle exactly as labeled by the pharmacy.
  • If you experience concerning effects, pause use and contact your clinician.

PT-141 (bremelanotide), PDE5 inhibitors like sildenafil, and Vyleesi® each work differently. PT-141 targets central desire and arousal pathways, while PDE5 inhibitors focus on blood-flow effects. Vyleesi® is an on-demand option specifically approved for certain women. In women, PT-141 may be considered when appropriate, whereas PDE5 inhibitors are typically not indicated, and Vyleesi® serves a clearly defined female indication. In men, PT-141 may also be considered when clinically appropriate, while PDE5 inhibitors are widely used; Vyleesi® does not apply to men. All three options are used on-demand, depending on the individual’s needs and provider guidance.

 
 

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Hit your health goals safely & affordably in 3 simple steps

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Complete a quick form and meet with a licensed medical provider 100% online. They’ll determine if a personalized treatment plan is right for you.

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If eligible, your custom prescription will be shipped directly to your door, fast and free.

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We’ll be with you every step of the way, with regular check-ins and on-demand medical support to keep you on track.

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Discover how PT-141 can enhance desire, boost arousal, and bring your intimacy back into harmony. All plans include:

PT-141 nasal spray - Bremelanotide

PT‑141 Nasal Spray (Bremelanotide)

$139 first month*

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Increase desire with PT-141 nasal spray

Frequently Asked Questions About Pt-141

How long does PT‑141 take to work?

Timing varies, but many adults plan for a window beginning within about an hour when used as directed. Your clinician can help you plan timing.

Commonly Reported
  • Nausea
  • Flushing, warm feeling
  • Headache
Who Should Avoid
  • People with uncontrolled high blood pressure or significant cardiovascular disease
  • Anyone advised by a clinician not to use PT‑141
  • Individuals with known allergies to any ingredient

Duration varies by individual. Your clinician will advise on expected timelines and safe frequency.

Yes. PT‑141 requires a prescription. Telehealth clinicians determine eligibility based on your health profile and goals.

PT‑141 can be appropriate for some adults when prescribed, but it isn’t right for everyone. Safety review includes blood pressure, heart history, medications, and allergies.

Your clinician can evaluate if PT‑141 is appropriate for your specific situation. Availability and indications may differ by product and state.

Nausea is most commonly reported, with possible flushing or headache. If side effects concern you, contact your clinician.

Interactions and blood‑pressure effects matter. Do not combine without asking your clinician for personalized guidance.

Your prescription will include frequency limits. Do not exceed one on‑demand dose in any 24‑hour period. Follow monthly limits as directed.

Both are on‑demand forms. Choice depends on your comfort and clinical guidance. Your prescriber will recommend based on your profile.

Orders ship discreetly through partner pharmacies with cold‑chain or other handling as labeled when required.

PT‑141 (bremelanotide) is intended for adult, premenopausal women with acquired, generalized hypoactive sexual desire disorder (HSDD)— low sexual desire that causes distress and isn’t explained by another medical or psychiatric condition. Eligibility is decided through a structured telehealth evaluation with a licensed US clinician who reviews your history, medications, mood, relationship context, cardiovascular risks, and goals. If PT‑141 is an appropriate option, we’ll discuss benefits and trade‑offs, dosing, and what to monitor. If it’s not a fit, we’ll offer evidence‑based alternatives (behavioral approaches, couples or sex therapy, flibanserin, hormonal options when appropriate) and carefully explain why. Our process is patient‑first, no‑pressure, and always US‑compliant.

In the United States, bremelanotide is FDA‑approved under the brand Vyleesi specifically for treating acquired, generalized HSDD in premenopausal adult women. It is not approved for men or for cosmetic purposes. During your visit we’ll confirm clinical criteria, discuss safety information (including the risk of nausea and temporary increases in blood pressure), and review dosing limits. If appropriate, your clinician may prescribe the FDA‑approved product and coordinate pharmacy fulfillment in your state.

No. PT‑141 through our service is not for men. US labeling for bremelanotide (Vyleesi) limits indication to premenopausal adult women with HSDD. We do not prescribe it for tanning, bodybuilding, or non‑medical uses. If you’re seeking support for erectile function or low desire in men, we’ll direct you to evidence‑based alternatives evaluated by a clinician (for example, PDE‑5 options when medically appropriate, or a broader evaluation for libido concerns).

PDE‑5 medicines (e.g., sildenafil, tadalafil) primarily increase blood flow to help erections in men; they don’t treat reduced desire. PT‑141 activates melanocortin receptors within the central nervous system thought to influence sexual desire and arousal pathways in women with HSDD. It’s used on an as‑needed basis, not daily, and the primary endpoints differ from PDE‑5 drugs. Your clinician can explain whether PT‑141, flibanserin, behavioral therapy, or other options match your goals and medical profile.

Typical on‑label dosing is a single 1.75 mg subcutaneous injection, as needed, at least 45 minutes before anticipated sexual activity. Many people notice effects within 45–90 minutes. Do not exceed one dose in 24 hours and do not exceed eight doses per month. Your clinician will go over timing strategies, safe injection technique, and how to decide whether to try again on another day if the first experience doesn’t align with expectations.

 Effects are variable, but some patients report benefits for several hours after a dose. Because PT‑141 is used as‑needed, your clinician will help you plan timing so the window of effect aligns with your schedule. Keep in mind that mindset, relationship dynamics, privacy, and stress levels also shape outcomes; we encourage a whole‑person approach rather than relying on medication alone.

Clinician note: The most commonly reported side effect is nausea, especially with initial doses. Other reactions can include flushing, headache, injection‑site reactions, and sometimes vomiting. Nausea typically improves with subsequent uses for many patients. Your clinician will review warning signs that require medical attention and provide practical tips (hydration, light snack beforehand, dose timing away from heavy meals). We’ll also discuss when to stop and contact the team.

Here’s what to know: PT‑141 can cause transient increases in blood pressure and decreases in heart rate shortly after dosing. For this reason, we screen for cardiovascular risks and generally avoid use in those with uncontrolled hypertension or known cardiovascular disease. If you have a history of high blood pressure that’s well controlled, your clinician will discuss risks, monitoring, and whether PT‑141 is appropriate for you.

Here’s what to know: Contraindications and reasons to avoid PT‑141 include: uncontrolled hypertension, significant cardiovascular disease, pregnancy, and hypersensitivity to components. Use caution with severe liver or kidney impairment. A careful medication and medical history review happens during your telehealth visit so you can make an informed, safety‑first decision with your clinician.

Clinician note: PT‑141 is not recommended during pregnancy or while breastfeeding. If you are pregnant, trying to conceive, or breastfeeding, please tell your clinician so we can discuss safer alternatives. We’ll also review reliable contraception and your broader health priorities to align care with your plans.

Key point: There are no widespread, common drug‑drug interactions that affect most patients, but your individual list matters. Bring all prescriptions, over‑the‑counter products, and supplements to the visit. We review alcohol and caffeine use as well. Your clinician will tailor guidance to your medical history and explain any specific combination to avoid or monitor.

In brief: Nausea is common with first‑time use. Practical strategies include a light snack 30–60 minutes before dosing, avoiding large or fatty meals immediately before the injection, staying hydrated, and having ginger or anti‑nausea remedies recommended by your clinician on hand. Many patients report that nausea diminishes with subsequent uses. If you vomit or feel unwell, pause and contact our team for guidance before trying again.

PT‑141 is administered subcutaneously—just under the skin—with a small needle. We provide a step‑by‑step guide and teach you injection hygiene: clean hands, clean site, correct angle, slow and steady delivery, proper sharps disposal, and site rotation. If needles make you anxious, tell us; we can coach you through techniques that make the experience more comfortable and safe.

Quick take: Common subcutaneous injection sites include the abdomen (at least two inches from the navel), outer thigh, and upper arm. Rotate locations to minimize irritation and bruising. Avoid areas with scars, rashes, or cuts. We’ll give you an illustrated guide with simple checklists you can follow at home.

Summary: Absolutely. Medication works best alongside a whole‑person approach. For many patients, brief counseling, sex therapy, or couples‑based strategies improve communication, reduce anxiety, and help align expectations—amplifying the benefits of PT‑141. We can refer you to licensed therapists when appropriate or share evidence‑based exercises you can start immediately.

The bottom line: Flibanserin (Addyi) is a daily oral therapy for HSDD in premenopausal women with specific alcohol‑related restrictions; PT‑141 is an as‑needed injectable used before anticipated sexual activity. The risk/benefit profiles and side‑effect patterns differ. Your clinician can help you compare both options—as well as non‑drug approaches—to choose what best aligns with your health and lifestyle.

In brief: A single experience may not reflect the full response. Ensure correct timing (at least 45 minutes prior), use a calm, low‑pressure setting, and try again on a different day if your clinician agrees. If you consistently see little benefit, we’ll reassess dose timing, expectations, and alternatives—never pushing a treatment that isn’t helping you.

Do not exceed one dose in a 24‑hour period, and do not exceed eight doses in a month. These limits are part of the safety guidance to reduce risks such as nausea and blood‑pressure changes. If you feel you need more frequent use, check in with your clinician to reassess goals and safer options.

Coverage varies. Some plans may reimburse the telehealth visit, while medication coverage differs by insurer and pharmacy benefit manager. We provide itemized receipts and can help you submit claims where applicable. If out‑of‑pocket, we’ll explain pricing clearly before you commit—no surprises.

Here’s what to know: We separate the clinical visit fee from medication costs to keep billing transparent. Before your appointment you’ll see estimated visit pricing; after your clinician determines eligibility and writes an e‑prescription, the dispensing pharmacy will share medication pricing and shipping options available in your state.

 Yes. We use HIPAA‑aligned systems, encrypted messaging, and strict access controls. Your records are visible only to the care team involved in your treatment unless you authorize sharing. We never sell your medical data to advertisers—your privacy is non‑negotiable.

We serve US patients in select states through licensed clinicians. Availability expands as our network grows. Enter your ZIP code during signup to confirm coverage and see next‑available appointment times in your area.

 Once your prescription is approved, most partner pharmacies ship within 1–3 business days when in stock. You’ll receive tracking and discreet packaging. Weather or carrier delays can occur; our support team monitors shipments and will intervene if problems arise.

 In many states we offer same‑day or next‑day telehealth visits, including some evening and weekend slots. If you need a specific time, book in advance—we’ll display real‑time openings during checkout.

 You meet with a real, US‑licensed clinician who reviews your questionnaire, conducts a structured video or audio visit, answers questions, and—if appropriate—writes an e‑prescription. We do not auto‑approve requests, and we never bypass safety criteria.

Most visits take 10–20 minutes. Expect questions about medical history, mood, relationship context, prior treatments, and safety screening (blood pressure, kidney/liver issues, pregnancy plans). Bring a current medication list to streamline decisions.

 PT‑141 targets desire pathways and may also influence arousal. Orgasmic function is multifactorial; some patients perceive broader benefits, while others focus on desire alone. We set realistic expectations and often integrate non‑pharmacologic strategies for the best results.

Hypoactive sexual desire disorder is persistent, distressing low sexual desire not better explained by another condition, medication, relationship issue, or life event. Diagnosis is clinical—based on history and validated tools—after ruling out contributing factors. We take time to listen and create a plan aligned with your values.

We routinely screen for mood and anxiety conditions. PT‑141 isn’t a treatment for depression or anxiety, but those conditions can influence sexual desire. We’ll coordinate care with your primary or mental‑health clinician, adjust plans if needed, and ensure your safety and comfort come first.

Focal skin or gum darkening has been reported with bremelanotide in a small percentage of patients, sometimes persistent. The risk may increase with higher frequency of use and in those with more baseline pigmentation. We’ll review signs to watch for and when to stop and contact us.

 PT‑141 is not labeled for postmenopausal women. If you’re postmenopausal and experiencing low desire, we’ll explore other options—including hormonal strategies when appropriate, flibanserin, behavioral therapy, and addressing contributing medical factors—always tailored to your goals.

Some patients use PT‑141 alongside hormone therapy under clinician supervision. Because hormone therapy has its own indications and risks, we’ll coordinate to ensure the combination makes sense for your history and that you understand benefits and trade‑offs.

 Traveling within the US with properly labeled medication is generally permissible. Keep PT‑141 in original packaging, carry a copy of your prescription, and follow storage guidance. If you’re flying, place it in a carry‑on with any cooling packs allowed by TSA rules.

 Uncontrolled hypertension is a reason to avoid PT‑141. If your blood pressure is well controlled and you have no major cardiovascular disease, your clinician may consider PT‑141 after a risk discussion. We’ll emphasize dose limits and when to stop and seek care.

Severe kidney or liver impairment warrants caution or avoidance. Tell your clinician about any prior labs or diagnoses—together we’ll choose a plan that fits your health profile without compromising safety.

 Follow pharmacy labeling. Many prefilled products are stored at controlled room temperature away from light and moisture; some require refrigeration before first use. Do not freeze. We’ll include clear instructions with your shipment and in your online portal.

 Standard workplace drug screens don’t test for bremelanotide. If you’re an athlete or subject to special testing, review anti‑doping policies and ask your organization—rules vary and are outside our control.

 If you missed the 45‑minute pre‑planning window, you can delay intimacy or plan for another day—do not “double dose.” Keep within the single‑dose per 24‑hour and eight‑per‑month limits, and contact us if timing repeatedly feels tricky; we can suggest scheduling strategies.

 PT‑141 is as‑needed, not scheduled like a weekly maintenance drug. Some people find a rhythm (e.g., weekends), but you must respect safety limits. If you feel you need frequent dosing, we’ll reassess whether this is the best option for you.

When appropriate, we prescribe the FDA‑approved brand (Vyleesi). As a US‑compliant clinic, we do not dispense compounded bremelanotide when it would be essentially a copy of a commercially available approved drug, unless permitted by law (e.g., during an FDA‑recognized shortage). Your clinician will explain options consistent with federal and state rules.

Key point: Yes—your visit notes, diagnosis, and prescriptions are saved in your secure portal. You can download records or share them with your other clinicians upon request.

Yes. Secure messaging lets you ask questions, report side effects, and request refills when appropriate. We encourage periodic check‑ins to ensure benefits outweigh risks and to adjust your plan as life changes.

 For urgent or severe reactions, use local emergency services or urgent care immediately. For non‑urgent issues after hours, send us a message; we typically respond the next business day and will escalate sooner when appropriate.

We provide care for adults 18+. We do not evaluate or treat minors for PT‑141 under any circumstances.

 If cost is a concern, ask our team about savings opportunities, pharmacy options, or payment plans. We strive for transparent pricing and will never start a medication without your informed consent regarding costs.

No. We do not prescribe or supply any drug for tanning or cosmetic pigment changes. Requests for “melanotan‑style” products are declined; they are not FDA‑approved and fall outside our medical practice standards.

 There’s no evidence that PT‑141 causes physiologic dependence. That said, any as‑needed therapy should be used thoughtfully within dosing limits and in the context of broader relationship and mental‑health well‑being.

Some people experience nausea, dizziness, or flushing. Until you know how you respond, avoid driving or operating machinery after a dose. Plan your first uses in a calm, safe environment.

 PT‑141 is not a fertility treatment and isn’t recommended while trying to conceive. Discuss pregnancy plans with your clinician so we can align timing and safer alternatives.

Headache can occur with PT‑141. If you have a migraine history, discuss frequency and triggers with your clinician. We’ll weigh risks and create a plan that includes non‑drug strategies to reduce triggers when possible.

 Yes—pelvic floor physical therapy, mindfulness‑based practices, and sensate‑focus exercises can all complement PT‑141 by addressing discomfort, anxiety, or muscle tension that can undermine desire and arousal.

We route prescriptions only to vetted US pharmacies. We do not source from informal markets, social media, or overseas suppliers. This safeguards authenticity, dosing accuracy, and proper storage/handling.

 Depending on your state and the pharmacy network, you may have local pickup options. Otherwise, we ship discreetly with tracking. We’ll show choices after your clinician finalizes the prescription.

 Clinical visit fees cover your clinician’s time and are generally non‑refundable once the evaluation occurs. If a technical issue prevents your visit, we’ll make it right. Medication refunds follow the dispensing pharmacy’s policies and federal rules for prescription products.

We do not sell your medical data. Our systems use encryption, role‑based access, and audit logs. You control who sees your records, and you can request export or deletion of certain non‑clinical data as permitted by law.

Share prior records through our secure portal, and we’ll pick up from there. If you’re switching because of side effects or limited benefit, we’ll reassess and consider alternatives rather than repeating the same plan.

Alternatives can include flibanserin (daily oral), targeted hormone therapy when indicated, psychosexual counseling, addressing contributing medical issues (e.g., thyroid, mood), and relationship‑focused strategies. We’ll match options to your history and preferences—no one‑size‑fits‑all approach.

Most patients follow up within 4–8 weeks after starting, then periodically based on response, side effects, and life changes. We’ll schedule a cadence that fits your needs and complies with state regulations.

Contact support immediately. We’ll coordinate with the pharmacy and carrier to investigate and resolve, keeping you in the loop with clear next steps. Your safety and access are our priorities.

You can manage renewals, refills, and future appointments inside your portal. Cancel any auto‑refills before the next processing date to avoid charges. We keep policies transparent and easy to find.

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Clinically Proven & Lab-Tested for Safety

Every prescription is prepared by a licensed U.S. pharmacy and independently tested by FDA and DEA registered laboratories for purity, potency, sterility, and stability before shipping.

Potency

Tested every 3–6 months to verify ±5% active ingredient accuracy.

Sterility ​

Every batch is tested, free from contaminants, bacteria, and meets USP <797> standards.

Endotoxicity

Each batch is tested for endotoxins and sterility to meet USP <85> safety limits.

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